Rosuvastatin (Crestor) is a high-potency statin that reduces LDL cholesterol by up to 63% at maximum doses. It is minimally metabolized by CYP3A4, resulting in fewer drug interactions than atorvastatin.
Available as generic tablets from 5 to 40 mg, rosuvastatin is particularly useful in patients on medications that interact with the CYP3A4 pathway, including several HIV antiretrovirals and immunosuppressants.